The coronavirus pandemic has triggered a massive, worldwide effort to develop effective vaccines and treatments. With a previous focus on cancer, Pascal’s scientists directed their efforts to discovering a cannabinoid-based treatment for COVID-19. Pascal made the decision to test cannabinoids…
Read MorePre-BCR Antibodies for Leukemia Pascal is developing antibodies against the pre-B cell receptor (pre-BCR) for B cell precursor acute lymphoblastic leukemia (BCP-ALL). The pre-BCR comprises a heavy chain paired with a surrogate light chain. The two components of the surrogate…
Read MoreCannabinoid-based therapeutic for glioblastoma PAS-403 (previously known as ST-403) is a mitosis inhibitor that blocks cell division. The cannabinoid-based product is undergoing development for the treatment of glioblastoma and brain metastases originating from other cancers. Several mitotic inhibitors approved for…
Read MoreCannabinoid-based therapeutic for restoring immune recognition Advanced cancers typically become invisible to the immune system, thus allowing them to evade elimination. PAS-393 is a cannabinoid designed to restore the immunogenicity of tumor cells, thus rendering these cells once again susceptible…
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