Pre-BCR Antibodies for Leukemia Pascal is developing antibodies against the pre-B cell receptor (pre-BCR) for B cell precursor acute lymphoblastic leukemia (BCP-ALL).  The pre-BCR comprises a heavy chain paired with a surrogate light chain. The two components of the surrogate…

Cannabinoid-based therapeutic for glioblastoma PAS-403 (previously known as ST-403) is a mitosis inhibitor that blocks cell division. The cannabinoid-based product is undergoing development for the treatment of glioblastoma and brain metastases originating from other cancers. Several mitotic inhibitors approved for…

Cannabinoid-based therapeutic for restoring immune recognition Advanced cancers typically become invisible to the immune system, thus allowing them to evade elimination. PAS-393 is a cannabinoid designed to restore the immunogenicity of tumor cells, thus rendering these cells once again susceptible…